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Product Detail & Benefits


Glucosamine sulfate is classified as an amino sugar, a type of carbohydrate used for structural tissues instead of as an energy source. It is the basic building block/raw material in joint cartilage, ligaments, and tendons. Glucosamine sulfate plays a major role in the synthesis of collagen, cartilage, bone, skin, and various lubricating fluids in joints. Glucosamine sulfate helps promote elasticity of joint movement and also functions as a mild anti-inflammatory.

Chondroitin sulfate is a natural component of several tissues in the body. Like glucosamine, chondroitin sulfate is one of the important building blocks for the repair of damaged cartilage. One of chondroitin sulfate's important functions is its ability to block the activity of enzymes that break down cartilage. This helps reduce inflammation and protects cartilage from further damage. Chondroitin sulfate also promotes lubrication and cushioning in the joints.

Methylsulfonylmethane, better known as MSM, is a metabolite of dimethylsulfoxide (DMSO), a well-known solvent, which has been used topically as an analgesic with anti-inflammatory properties. MSM is an organic form of sulfur, which is necessary for proper synthesis and maintenance of tissues such as skin, hair, nails, tendons and cartilage.

Tissue Rejuvenator's Enzyme Blend of peptidase, bromelain, papain, amylase, lipase, cellulase, and phytase not only aids in the complete absorption of the nutrient components in the product, it provides its own potent anti-inflammatory benefits.

Boswellia serrata is an Ayurvedic herb with anti-inflammatory properties. Its primary active ingredients are triterpene acids, which may also be useful for relief from exercise-induced breathing difficulties.

Devil's Claw is a South African herb containing substances called iridoid glycosides that have anti-inflammatory properties. It is also purported to temporary relief of mild stomach upset.

Yucca Root is frequently used to offer temporary relief from osteoarthritis and rheumatoid arthritis symptoms. It contains high levels of beneficial phytochemical compounds known as saponins, which may provide anti-fungal and antibacterial benefits as well.

Turmeric (Curcuma longa) contains a substance called curcumin, which has not only anti-inflammatory properties but also provides liver support and antioxidant properties as well.

Quercetin is a water-soluble flavonoid typically found in onions, apples, leafy vegetables, and other food sources. It has both antioxidant and anti-inflammatory properties.

Undenatured Type II Collagen (UC-II™) is a patented, extensively studied dietary ingredient derived from chicken sternum cartilage. Through a complex process called oral tolerization, UC-II™ works with the immune system to promote healthy joints and increase joint mobility and flexibility. (U.S. Patents 5,645.851, 5,637,321, 5,529,786, and 5,750,144). UC-II™ is a trademark of InterHealth N.I.


Extra Benefits:
Turmeric, one of the components in Tissue Rejuvenator, in addition to being a powerful anti-inflammatory, is also a well-known antioxidant and anti-carcinogenic agent.

If you're injured and can't wait to get back into action, or if you're trying to prevent joint and tissue injuries, add Tissue Rejuvenator to your order list. It's a powerful, dual-purpose product, supplying your body with nutrients that provide the raw materials it needs to promote rapid tissue repair, while also helping to reduce inflammation, soreness, and pain-without requiring you to over-rely on NSAIDs (non-steroidal anti-inflammatory drug). Remember, as with all our products, Tissue Rejuvenator, the combined rebuild-relieve joint product, is fully guaranteed. If it doesn't work for you, you get a full refund. Period.

Nutrition Labels:

Tissue Rejuvenator
Supplement Facts
Serving Size 4 Capsules
Amount Per Serving % Daily Value*
Glucosamine Sulfate 500mg
Chondroitin Sulfate 500mg
MSM (Methylsulfonylmethane) 500mg
Proprietary Enzyme Blend (peptidase, bromelain, papain, protease, amylase, lipase, cellulase, and phytase) 400mg
Boswellia Serrata 400mg
Devils Claw 200mg
Yucca Root 100mg
Turmeric (Curcuma longa) Root Extract 100mg
Quercetin (Saphora Japonica Source) 20mg
Undenatured Type II Collagen 5mg
* The Percent Daily Values are based on a 2,000 calorie diet. Your daily values may be higher or lower depending on your calorie needs.
† Daily Value not established.
Other Ingredients: Stabilized Rice Bran, Vegetable Capsules (plant cellulose and water)

Fueling & Usage Tips

Tissue Rejuvenator: Promote repair safely and naturally!

Tissue Rejuvenator: Promote repair safely and naturally!

Tissue Rejuvenator has quickly become one of Hammer Nutrition's top-selling supplements, and with good reason - it works!

Tissue Rejuvenator's Glucosamine Sulfate & Chondroitin Sulfate

Tissue Rejuvenator's Glucosamine Sulfate & Chondroitin Sulfate

What do you say in response to the NEJM study on Glucosamine and Chondroitin. They found that it only beat the placebo for severe joint pain.

Tissue Rejuvenator

Tissue Rejuvenator

Maintain healthy joints safely and naturally

Tissue Rejuvenator - AES vol 13.14

Tissue Rejuvenator - AES vol 13.14

Stay in the game . . . safely and naturally!

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Product Reviews

Rated 5 out of 5 by from Animals Too? I have used many Hammer products over the years with much success. Then one day my dog Mia (a pittbull) tore her ACL. The outlook from the vet was not good. They even expected her to need surgery (expensive surgery). I figured why not, if its good for me why not try it on her. Well she recovered totally and very quick. The vets were amazed as was I. Was it the TR? I have no other explanation as to how she healed so quickly. Has been several years and no further problems (knock on wood). Now my new English bull dog is a little over a year and having knee (joint) problems. Just bought a bottle for her. Will keep fingers crossed and let you know how things turn out.
Date published: 2014-11-27
Rated 5 out of 5 by from Believe it. It works! I was on the verge of calling in sick and going to the doctor for my knee pain. Off the shelf Clucosamine\Chondroitin\MSM just was not working. Then I thought to try Tissue Rejuvenator. 4 before bedtime, woke up feeling no pain, just a little stiffness. Continued 4 am and 4 pm dosage until bottle was empty I have no pain or stiffness. I saw a co-worker limping. He told me his knee bothers him. I provided him with one of my bottles of Rejuvenator. Worked for him exactly as it did for me. He then recommended the product to another co-worker. Worked for him also. We are letter carriers. I personally walk 13 miles a day. This product is very effective!
Date published: 2015-07-30
Rated 5 out of 5 by from I thought, "eh... why not?" 48 y/o former soldier with rucksack wear at both shoulders and lumbar. I had back surgery back in 2001 and ache in my back was a constant companion. Shoulder ROM was limited. Not so much anymore :-) Move over Vicodin, Tramadol, flexaril, meloxicam, methocarbanol, feldene, motrin, soma, naproxen and all the other pharmaceuticals prescribed by the VA. My quality of life has improved. Thank you Hammer guys for putting out a legit product. Going to put the AO caps in the mix. #rollingandriding
Date published: 2016-04-06
Rated 3 out of 5 by from Not sure how it helps. I am about 2/3 finished with my first bottle (120 pills). I cannot put my finger on it yet. I've been taking this every morning and evening but I am also taking Recoverite after every workout. I do feel great and soreness is not an issue anymore but I think it's not the TR but rather the Recoverite. Before taking any Hammer supplements I used to have an ugly pain in my both shoulder blades. Six weeks taking all these products, the pain somehow receded by a considerable amount, but did not disappear. I work out 5-6 days a week.
Date published: 2014-03-20
Rated 5 out of 5 by from Good stuff for the knees and inflammation I find this product is really useful for at the start of riding season when your knees get sore after every ride and need time to get back into the riding rhythm. I recently pushed myself to take on a challenge of a monstrous hill in my area for the first time. I managed to conquer it but I paid the price later with days of aches and pains from inflammation. I was taking Ibuprofen 3-4 times a day for 4 days with no end in sight. I took four of these and had some relief. I woke up the next day and wasn't as achy as I had been. I took it again and by third day I didn't even need any pain killers. It's been so effective for me that I've decided to make it a part of my normal after-workout regiment.
Date published: 2015-07-05
Rated 5 out of 5 by from Fantastic suppplement I have had the surgery to correct 2 herniated discs in my lower back and now I suffer from severe degenerated discs in those locations. I have been taking this for a few weeks, hoping to not have to take the anti-inflammatory meds any more. It is working. I am very happy with this product. It has greatly reduced my daily pain, and it has increased my mobility and I am able to function at a higher level. I would recommend this product to anyone who has joint problems
Date published: 2014-03-11
Rated 1 out of 5 by from No help at all I purchased this product in hopes of cutting down on some of the ibuprofen I take daily for soreness and injury's sustained in tennis. I would love to say the product work But could feel no relief of pain or soreness. Last night I Looked at the ingredients and found them to be most of the ones I have read have little or no affect... Like so Many supplements, I feel they are a waste of money.
Date published: 2014-05-28
Rated 5 out of 5 by from Great Product! I love Tissue Rejuvenator! I was racing the LovIt 100K in February when I rolled my ankle badly twice during the race. I saw my ortho after the race where I was informed I significantly tore 3 major ligaments in my ankle. When I visited her again 3 weeks later she couldn't believe how fast I was healing. I was able to fully recover and race the Ouchita 50M in April where I took 1st female and 2nd overall. I owe my quick recovery to tissue Rejuvenator.
Date published: 2015-10-09
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