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Product Detail & Benefits


Glucosamine sulfate is classified as an amino sugar, a type of carbohydrate used for structural tissues instead of as an energy source. It is the basic building block/raw material in joint cartilage, ligaments, and tendons. Glucosamine sulfate plays a major role in the synthesis of collagen, cartilage, bone, skin, and various lubricating fluids in joints. Glucosamine sulfate helps promote elasticity of joint movement and also functions as a mild anti-inflammatory.

Chondroitin sulfate is a natural component of several tissues in the body. Like glucosamine, chondroitin sulfate is one of the important building blocks for the repair of damaged cartilage. One of chondroitin sulfate's important functions is its ability to block the activity of enzymes that break down cartilage. This helps reduce inflammation and protects cartilage from further damage. Chondroitin sulfate also promotes lubrication and cushioning in the joints.

Methylsulfonylmethane, better known as MSM, is a metabolite of dimethylsulfoxide (DMSO), a well-known solvent, which has been used topically as an analgesic and anti-inflammatory. MSM is an organic form of sulfur, which is necessary for proper synthesis and maintenance of tissues such as skin, hair, nails, tendons and cartilage. MSM has been reported to reduce arthritic joint pain, enhance wound healing, and reduce allergic symptoms.

Tissue Rejuvenator's Enzyme Blend of peptidase, bromelain, papain, amylase, lipase, cellulase, and phytase not only aids in the complete absorption of the nutrient components in the product, it provides its own potent anti-inflammatory benefits.

Boswellia serrata is an Ayurvedic herb that has been extensively used as an anti-inflammatory for the treatment of arthritis. Its primary active ingredients are triterpene acids, which may also be useful for treating exercise-induced asthma and irritable bowel syndrome.

Devil's Claw is a South African herb containing substances called iridoid glycosides that have anti-inflammatory properties. It is also purported to help relieve mild stomach upset.

Yucca Root is frequently used to combat osteoarthritis and rheumatoid arthritis symptoms. It contains high levels of beneficial phytochemical compounds known as saponins, which may provide anti-viral, anti-fungal, and antibacterial benefits as well.

Turmeric (Curcuma longa) contains a substance called curcumin, which has not only anti-inflammatory properties but also liver protecting, antibiotic, and antioxidant properties as well.

Quercetin is a water-soluble flavonoid typically found in onions, apples, leafy vegetables, and other food sources. It is both a potent antioxidant and anti-inflammatory and may also act as an antihistamine.

Undenatured Type II Collagen (UC-II™) is a patented, extensively studied dietary ingredient derived from chicken sternum cartilage. Through a complex process called oral tolerization, UC-II™ works with the immune system to promote healthy joints and increase joint mobility and flexibility.


Extra Benefits:
Tumeric, one of the components in Tissue Rejuvenator, in addition to being a powerful anti-inflammatory, is also a well-known antioxidant and anti-carcinogenic agent.

If you're injured and can't wait to get back into action, or if you're trying to prevent joint and tissue injuries, add Tissue Rejuvenator to your order list. It's a powerful, dual-purpose product, supplying your body with nutrients that provide the raw materials it needs to promote rapid tissue repair, while also helping to reduce inflammation, soreness, and pain-without requiring you to over-rely on NSAIDs (non-steroidal anti-inflammatory drug). Remember, as with all our products, Tissue Rejuvenator, the combined rebuild-relieve joint product, is fully guaranteed. If it doesn't work for you, you get a full refund. Period.

Nutrition Labels:

Tissue Rejuvenator
Supplement Facts
Serving Size 4 Capsules
Amount Per Serving % Daily Value*
Glucosamine Sulfate 500mg
Chondroitin Sulfate 500mg
MSM (Methylsulfonylmethane) 500mg
Enzyme Blend (peptidase and bromelain, papain, protease, amylase, lipase, cellulase, and phytase) 400mg
Boswellia Serrata 400mg
Devils Claw 200mg
Yucca Root 100mg
Turmeric (Curcuma longa) Root Extract 100mg
Quercetin (Saphora Japonica Source) 20mg
Undenatured Type II Collagen** 5mg
* The Percent Daily Values are based on a 2,000 calorie diet. Your daily values may be higher or lower depending on your calorie needs.
† Daily Value not established.
**UC-II brand undenatured type II collagen (U.S. Patents 5,645.851, 5,637,321, 5,529,786, and 5,750,144). UC-II™ is a trademark of InterHealth N.I.
Other Ingredients: Stabilized Rice Bran, Vegetable Capsules (pullulan and water)

Nutrition & Usage Tips

Tissue Rejuvenator (AES vol 13.14)

Tissue Rejuvenator (AES vol 13.14)

Stay in the game . . . safely and naturally!

Tissue Rejuvenator's Glucosamine Sulfate & Chondroitin Sulfate

Tissue Rejuvenator's Glucosamine Sulfate & Chondroitin Sulfate

What do you say in response to the NEJM study on Glucosamine and Chondroitin. They found that it only beat the placebo for severe joint pain.

Tissue Rejuvenator

Tissue Rejuvenator

Maintain healthy joints safely and naturally

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Product Reviews

Rated 5 out of 5 by from Great product Have been ice/advil treatment plan for a while now, and figured I should try Tissue Rejuvenator. TR will now be my goto not advil, it really works that good.
Date published: 2014-04-19
Rated 5 out of 5 by from actually works! This did exactly what it claims! I was surprised how much better i felt after using it. im an ultra runner and i hate taking NSAIDS ever, so this is perfect for me. Ide been having annoying hip pain (piriformis issues) for a year, and this has completely fixed the muscle-swelling problem and so now i also do not have the sciatic nerve pain either that was a result of the piriformis swelling and pressing on it. Im thrilled with this and hope they never stop making it! :)
Date published: 2014-04-13
Rated 5 out of 5 by from Great product my neice gave me my first bottle Great product my neice gave me my first bottle. I have taken it the last six months after my first and second total knee replacement. I didn't really know how well they helped with healing, inflamation and pain until I ran out. I very soon realized that I needed to order more and take the recomended higher dosage for recovery. I highly recommend this product esspecially if you are in recovery mode.
Date published: 2014-04-08
Rated 5 out of 5 by from T/R for fast healing I took the recommended regimen ot Tissue Rejuvenator while recovering from rotator cuff surgery. My PT told me that, even at age 78, I am a fast healer. I attribute a great deal of that speed to T/R. Great stuff - I've ordered more and plan to take it regularly.
Date published: 2014-04-06
Rated 4 out of 5 by from Great for my knees and any other injury! I have been taking it for a couple of years.
Date published: 2014-03-31
Rated 5 out of 5 by from Must have - if you have joint pain! My husband has had pain in his knees for a number of years. I use hammer products with my running and saw the Tissue Rejuvenator and decided to purchase this for him. It has helped tremendously, he notices if he doesn't use the product - it's a keeper :)!
Date published: 2014-03-20
Rated 3 out of 5 by from Not sure how it helps. I am about 2/3 finished with my first bottle (120 pills). I cannot put my finger on it yet. I've been taking this every morning and evening but I am also taking Recoverite after every workout. I do feel great and soreness is not an issue anymore but I think it's not the TR but rather the Recoverite. Before taking any Hammer supplements I used to have an ugly pain in my both shoulder blades. Six weeks taking all these products, the pain somehow receded by a considerable amount, but did not disappear. I work out 5-6 days a week.
Date published: 2014-03-20
Rated 5 out of 5 by from Fantastic suppplement I have had the surgery to correct 2 herniated discs in my lower back and now I suffer from severe degenerated discs in those locations. I have been taking this for a few weeks, hoping to not have to take the anti-inflammatory meds any more. It is working. I am very happy with this product. It has greatly reduced my daily pain, and it has increased my mobility and I am able to function at a higher level. I would recommend this product to anyone who has joint problems
Date published: 2014-03-11
Rated 4 out of 5 by from Have been using this for awhile. Does help somewhat.
Date published: 2014-03-07
Rated 5 out of 5 by from Awesome Product I love this product, my knees love this product! My entire system functions with fewer aches and pains after a good workout.
Date published: 2014-03-02
Rated 5 out of 5 by from Best to be Pre-emptive This week I started strength conditioning with a coach and ordered TR because I knew I would be sore. On the 3rd day of training we did squats on a new machine I had never used before that worked ALL the muscles in my legs. I started TR that morning before doing the work and woke up the next day with no muscle soreness AT ALL. This surprised me greatly. Unfortunately, TR does not work for muscles that are already sore but that is to be expected. TR seems to be a great product if you stay one step ahead of muscle soreness. Use TR before the heavy days to prevent the pain. How I was not sore from the squats is amazing. It was my first day squatting with heavy weights in quite some time!! As a 44 year-old-athlete trying to stay on the podium in SUP races I need to train hard and stay pain free. TR and I are off to one heck of a great start in our long-term relationship!
Date published: 2014-02-27
Rated 5 out of 5 by from I noticed a difference in just a couple of days Both my knees have been bothering me this winter from running in preparation for a marathon next month. I've tried all the usual things like stretching, yoga, ice packs, and a supplement from the grocery store and none of them really made a difference. I felt a difference in just a couple of days with this product. I plan to stick to taking the supplement at least once a day until I feel recovered and may continue to take it as a preventative measure. I'm running the Big Three Marathons (London + Missoula + NYC) this year and want to enjoy every training run without the soreness.
Date published: 2014-02-27
Rated 5 out of 5 by from Tissue Rejuvenator (TR) Is it in my head or is it the formula?? I feel much much better since starting on TR a couple months ago. I had a knee tweak that I have needed 2 weeks to recover from in the past but this time it took 2 days. Crazy! How much was nature, nurture, different injury? I don't know, but I'm staying on TR!
Date published: 2014-02-21
Rated 5 out of 5 by from Great Results Works great!@ I don't leave home without it and you shouldn't either.
Date published: 2014-02-17
Rated 5 out of 5 by from I love this stuff Tissue Rejuvenator has helped me keep active. I don't know what I would do without it. I have far less pain and can run further since I started taking it.
Date published: 2014-02-10
Rated 5 out of 5 by from Tissue Rejuvenator keeps me running! I began using 3 TR caps per day after a knee surgeon told me to stop running until the surgical techniques to treat my issue were better and more reliable. That was over three years ago... I've competed in 35 triathlons since then and have placed number one or two in every race. I know for a fact that Tissue Rejuvenator has kept me running!
Date published: 2014-02-06
Rated 5 out of 5 by from The best suplement i have in a long time. I try different product and this one has the perfect formula, It is the best supplement i used in a long time, It really works with you joins and muscles, recuperation after extreme exercise is super fast and it works better if you used it with AO Booster.
Date published: 2014-02-04
Rated 5 out of 5 by from Best value Tissue rejuvenator allows me to keep moving. need it more now that I am over 60.
Date published: 2014-01-31
Rated 4 out of 5 by from helps me keep moving with decreased pain and I would recommend it to my friends
Date published: 2014-01-29
Rated 3 out of 5 by from I tried this product as an alternative to Ibuprofin for reducing joint swelling and pain. I'm still on the fence about TR. The pills are large, so digestibility is not great. I would prefer smaller pills. I'm not sure I get the relief from swelling and pain management I was after. So far I'd rate this product just average.
Date published: 2014-01-27
Rated 5 out of 5 by from I just had knee surgery and decided to start taking tissue rejuvenator a couple days after the operation and I believe the healing process has been revved up, I was taking TR before but only when I was mending cycling injuries, and I just felt TR was helping my injuries heal, thats why I decided to try with my knee surgery…. TR works
Date published: 2014-01-18
Rated 5 out of 5 by from works great! I tried Tissue Rejuvenator and fell in love with this product. It really works. No more aches and pains. I have normal muscle tightness after a half iron event but it also goes away by the next day.
Date published: 2013-12-05
Rated 5 out of 5 by from Tissue Rejuvenator As with all Hammer products, TR exceeds all expectations. The knee joint and elbow joint soreness has subsided since I began taking TR religiously.
Date published: 2013-12-04