LSA Caps’ Broccoli Extract Component

Its Benefits Extend Beyond the Liver!


Every four capsules of LSA Caps contains 350 mg of a super-concentrated broccoli extract. Like other cruciferous vegetables, broccoli is a rich source of an organic sulfur compound called sulforaphane, which helps increase levels of detoxification enzymes to protect the liver from damage.

Broccoli also contains another hugely beneficial compound known as indole-3-carbinol (I3C), which has applications for helping protect against numerous cancers, including colon cancer.

First author Dr. Amina Metidji of the Francis Crick Institute in London noted that I3C activates a specific protein, aryl hydrocarbon receptor (AhR), which carries signals to immune and epithelial cells (the latter is a type of cell that lines the surfaces of your body: skin, blood vessels, urinary tract, and organs). Dr. Metidji and other researchers determined that AhR is vitally important for repairing damage to the epithelial cells that line the intestinal tract

According to Dr. Metidji, “We studied genetically modified mice that cannot produce or activate AhR in their guts and found that they readily developed gut inflammation which progressed to colon cancer. However, when we fed them a diet enriched with I3C, they did not develop inflammation or cancer. Interestingly, when mice whose cancer was already developing were switched to the I3C-enriched diet, they ended up with significantly fewer tumors which were also more benign."

Dr. Gitta Stockinger, senior author and Group Leader at the Francis Crick Institute, states, “Seeing the profound effect of diet on gut inflammation and colon cancer was very striking. We often think of colon cancer as a disease promoted by a Western diet rich in fat and poor in vegetable content, and our results suggest a mechanism behind this observation. Many vegetables produce chemicals that keep AhR stimulated in the gut. We found that AhR-promoting chemicals in the diet can correct defects caused by insufficient AhR stimulation. This can restore epithelial cell differentiation, offering resistance to intestinal infections and preventing colon cancer.”

These findings are, as Dr. Stockinger so appropriately stated, profound in their implications. For activating AhR to help protect against colon cancer, and for so many other reasons, we need to make sure we include plenty of cruciferous vegetables in our diet. In addition to broccoli, other members of this food group include Brussels sprouts, arugula, cabbage, cauliflower, kale, radishes, and more.

To augment our intake of broccoli—providing the body with a potent dose of all its beneficial compounds, including I3C—we strongly suggest daily use of LSA Caps. As we have seen in this and other articles about the nutrients in this unique product, the benefits for LSA Caps extend far beyond liver health!